He is an ultra-endurance athlete, compulsive self-experimenter, and one of the most fascinating human beings I know. Throughout our lives, we experience different stressors that can cause strain on our mental health. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. , Almost anything youre going to eat is going to come with something thats going to slightly raise your temperature. Now hes a physician focused on the science of longevity. @bariweiss. Peter Attia, MD Intends To Win The Centenarian DecathlonHere's How August 2022 Huberman Lab Exercise, Nutrition, Hormones for Vitality & Longevity August 2022 Jocko Podcast Overcoming Stress, Sleep Deprivation, and the Darkness with Peter Attia January 2017 The Tim Ferriss Podcast Fasting, Metformin, Athletic Performance, and More (#398) And it didnt take me long to realize: not a chance in hell, for that exact reason. And so when I decided to leave, my first thought was actually to go to business school, because I really missed doing quantitative problem-solving. Almost anything youre going to eat is going to come with something thats going to slightly raise your temperature. So youre probably just in what are called theta waves. Now, in very low doses, which is what you would get if you were eating a piece of fruit, there is no problem in eating fructose. Now he's a physician focused on the science of longevity. If you learned something today, please share it with us! To me the more important question, Steve, and the one I spend more time thinking about, is: what do you do next time around? Dr. Peter trained for five years at the Johns Hopkins Hospital in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year. Hes spent the last few years being mentored by the top medical scientists and now hosts The Drive, a weekly, deep-dive podcast focusing on maximizing longevity by working on physical, cognitive, and emotional health. So I think when you say sugar, what you mean is added sugar. ATTIA: So there were a lot of things that were really upsetting me at the time. And that ketone was a substitute fuel for glucose and for fat. Most people, when they think of death, think of what we call cardiopulmonary death or what Im calling death-certificate death. But probably 80% of people have actually died one of the other deaths before they die a cardiopulmonary death. And so I do I think death is a very important part of the carbon cycle. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. LEVITT: And then you became obsessed with nutrition. But that can be carried by a group of philanthropists who can act quickly and take huge risk. Kudos to @SnoozyWeiss. And thats really about the highest praise I can offer anyone I know. He is the Co-founder and Chief Medical Officer of the fasting app Zero. Dr. Peter Attia received his medical degree from Stanford University in 2001. I dont do such silly things anymore. From 2012-2015, he . We only accept comment from posters who identify themselves. How often? I want to be able to hop over a three-foot fence. And so we slogged through this hour documentary on income inequality, basically, and I dont know, would we have been better off watching M.S.T. Fish Oil. I also had an additional conversation with Kevin Hall, PhD, one of the key researchers NuSI . And, by the end of that fast, I have very high levels of these things called ketones in my blood. You have to have one project which is 95 percent done and turned out well. The goal of his website is "to translate the cutting edge of the science of longevity (something roughly 0.01% of people are able to truly understand) into something that . ATTIA: Well, rigidity of thinking is generally a bad thing. And therefore it was just disjointed. Peter Attia, MD, is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. In fact, our conversation was so fascinating, that I decided to split it into two episodes! LEVITT: Yeah, absolutely. LEVITT: Oh, God. The four pillars of being a kick-ass 100-year-old. So how can we combat Type 2 diabetes? So, for example, if the argument is that the people who are most disadvantaged genetically will have the greatest benefit from change, the number I talk about with patients is probably five to seven years. So I know Ive got the time to get better and better. And I actually do find this topic interesting. And to me, we want to minimize that gap, right? Dr. Peter Attia is the founder of Attia Medical PC. Then a 90-minute nap in the middle of the day is restorative and additive to what you get at night. And actually, my model ended up working really well, but I was basically threatened that Id be fired if I ever did it again. And tell us about the longest period of time you ever spent in ketosis. And armed with your Nicorette gum, I figured, Look, this is going to be perfect. However, theres one disease that underlies all three of these. Peter Attia has dedicated his medical career to investigating the relationship between nutrition, obesity and diabetes. And I think its the perfect model, which is: let the government come in when its been de-risked. What a complete and total travesty. What does it do for you metabolically? But eating the quantities we do now, a mutation that we acquired many years ago starts to work against us. LEVITT: And how much fasting does a person have to do to start getting those benefits? A look at the effort to figure out why we're fat", "What Makes You So Smart, Peter Attia? What the three main pieces of our healthspan are. You got to do it.. Explore the list of the most recommended book titles suggested by Peter Attia . And you might say, Well, gosh, thats a lot of money. But in the scope of things, thats a trivial sum of money, if we could actually know that this much fasting could extend not just life, but improve quality of life that much. According to his website, Attia is "a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life and well-being." These credentials have given Attia unparalleled clout (along with David Sinclair) in this niche of influencers. Whats so good about being in ketosis? LEVITT: Yeah. It started very early. I think most people do get a bit of a cognitive jolt from it. So my guess is, theres some measure around helping them become better thinkers. and holds a B.Sc. So, again, evolution won. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease) while simultaneously improving healthspan (quality of life). And I missed that routine once in four years. . Dr. Peters goal is to reduce those early deaths as much as possible. I hope you loved this episode as much as I did. Right? Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. There is no evidence that the unique glucotype characterized by CGM differentially predicts outcomes compared to traditional metrics of glucose dysregulation; There is only weak evidence that glucose dysregulation as measured by OGTT, HbA1c, etc. Why dont we know the dose of fasting? But there was a brutal concussion I had. Peter Attia is a physician focusing on the applied science of longevity. My med school was at Stanford. And its a finding that basically predicts early onset of cardiovascular disease, which shouldnt have been a surprise to me because the list of men in my family who have died of cardiovascular disease is pretty long. It turns out that our bodies perform a lot of glucose disposal when we sleep, so sleep is incredibly important for preventing glucose from building up in our bloodstreams. As an Amazon Associate, Freakonomics may earn commissions from qualifying purchases made through links on this site. So it turns out that if you deprive the body of glucose, the body still goes through that same process. And then at lunch we would go to the University of Toronto I grew up in Toronto so wed go to University of Torontos weight room and do our really heavy lifting. Its a bit of luck and its having really good people around me who are really patient, who have been able to help nurture me back to a new way of thinking about life that is unrecognizable compared to the ethos that was 10 years ago. But you should be in the habit of listening to people talk about stuff that you dont agree with. Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. You sometimes need that distance from something. So, I think it puts N.I.H. Why the Oura ring sucks for tracking sleep and might be Chris Kresser is awful. Dr. Peter has an impressive career, but hes an even more impressive person in real life! Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. There are papers that have talked about and theorized that theres probably a 15-year extension that is plausible if everything is done right. And then you have to have a third project, which is like 75 percent done. For example, why werent we doing the contact tracing studies in subways and on airplanes and actually figuring out: what is a safe distance to be apart? In other words we have to learn how to manage the causes of stress and anxiety in our lives. Lets talk a little bit about the difference between lifespan and healthspan because theres a really key distinction between them. And I think most people do find a lot of benefit from it. So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. Freakonomics is a registered service mark of Renbud Radio, LLC. Im so grateful to him for taking the time to join me here on The School of Greatness! Which diseases are killing people the most and what to do about it. Peter Attia is the host of The Drive podcast and . He told me that a full sleep cycle takes about 90 minutes, so a nap of that length or longer is going to disrupt your sleep at night, since youll already have been through a full cycle. So I dont really chew it that much anymore, just out of sheer laziness. But I get a little bit worried that I dont know how to prepare them for a world that I dont understand. December 9, 2022, Designed by Elegant Themes | Powered by WordPress. And that seemed like a better option, given that I was already sitting on two hundred thousand dollars worth of debt. Im the only one left of anyone I knew when I was young who is still alive and functioning, which is obviously the only curse that comes with longevity. Donate here: DID THE DIETARY GUIDELINES (AND LOW-FAT DIETS, SUGAR, ETC.) By reducing the amount of carbohydrates we consume and by exercising, we reduce the amount of glucose were consuming and increase our muscle so that when we, consume glucose, our bodies have somewhere to put it. And white bread is generally depleted of anything of value. Little bit about the difference between lifespan and healthspan because theres a really key distinction between them of them funded! If you learned something today, please share it with us might be Kresser! Medical career to investigating the relationship between nutrition, obesity and diabetes on our mental health who can quickly! 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