Your thoughts? My Aussie/Pyrenees mix has had no issues with it, for instance. It should be given with food (as should any oral medication, really) to avoid a possible upset stomach. Your comment made me realize I might need to add another paragraph or two about Credelio. Dogs and cats . Also what can be used for giardia? The full indication is: "For dogs with, or at risk from, mixed external and internal parasitic infestations. HEARTGARD Plus real-beef chews are the delicious, #1 vet-recommended heartworm disease preventive - and pair perfectly with #1 vet-recommended NexGard (afoxolaner) chews. Basically, the idea is that heartworms take a few months to develop anyway, so every few months you get your dog tested instead of merely annually and ONLY treat for heartworms if bloodwork reveals that your dog has contracted heartworms. As an aussie, I like to assume he's an MDR1 carrier therefore can be reactive to certain meds. How can I prevent my dog from getting ticks? Two dogs were positive for D. immitis antigen but not MF on days 210 and 236. Im glad you found it helpful. Thank you! When sprinkled on a bug that has an exoskeleton (such as bed bugs, ants or fleas) it compromises their waxy coating so that their innards turn into teeny tiny bug jerky. If you do give Interceptor a try, its best practice to offer it with a meal to help avoid stomach upset. Just want to do what is best for them? We gave her the first dose in late February and there were no adverse side effects for Sugar. Thank you very much! Have you had any issues with Seresto? , Emily, thanks for a very helpful and informative article. Best of luck with your girl! Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug. Safety. We have two collies, Dash (8 yr old male) and Roxie (2.5 yr old female). I think Frontline Gold is very effective, and as far as I know there are no MDR1 concerns with it. From an MDR1 standpoint, Simparica is *technically* safe; but I am leery of it considering the FDA warning about isoxazolines (-laner medications) I discussed in the article. Thank you for this thorough and thoughtful work, Emily! According to Dog Aware, most flea and tick control medications have not been found to cause adverse effects when used as directed, but toxicity can occur iftopicalproducts areingested. This is why reading labels is so important. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Due to this fact, Pet Place warns: My personal veterinarian is MDR1-aware and only prescribes Interceptor (probably the safest heartworm med) and Credelio (an oral flea/tick medication alternative to Nexgard). Thank you for the useful information which is a little easier (clearer) to understand than most. (If you order online, keep in mind that the company will first have to contact your veterinarian for a prescription to be issued, which may slightly delay the shipping time.). After 1 emergency vet visit and a number of consultations with our primary care vet, we took him off simparica. I read that you you used this combination with success. Excellent research and well written article! Congratulations on the new kitten. 2022 Collie Chatter. It covers fleas, ticks, and heart worms. Thank you for your very informative article. She didnt recommend imodium because of the adverse reactions in dogs with mdr1. He had been taking the it for about 2-3 months. Please log in again. Another danger often lies in a treated dog being exposed to additional environmental pesticides, which can lead to an accidental overdose. Its safe for pregnant/nursing mother dogs and puppies as young as eight week. If a spot-on treatment is applied between the neck and shoulders as directed, no harm should befall a dog; but if its applied past the shoulders where a dog can reach with its tongue, that could definitely cause problems. Give Hollie Collie a good butt scratch or ear rub from me. Sounds like shes still going strong at her advanced age, and thats awesome. Yoshis vet initially recommended Credelio to us over other oral prescriptions since it is made by Elanco, the same company that makes Interceptor. Demonstrated 98.9% effectiveness against existing tick infestations in 48 hours . I dont know if youre on Facebook, but theres an awesome Facebook group called Border Collies Rock that can be a great forum for information. Substantially improves the clinical signs of Flea Allergy Dermatitis in dogs. Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. Hi there , thank you for putting this information up! Is credelio considered safe when using interceptor? Moxidectin, the heartworm-fighting portion of Advantage, is considered safe if the proper dosage is given monthly, but it did not test as well as either selamectin or milbemycin oxime in clinical trials, though it ranks above Ivermectin. My Vet told me Trifexis was safe to give them. (There are other places, but none more affordable that Ive found.) Good luck with everything, and please keep me updated on how your pup is doing! Thank you for all your research and article!! I have a toy Aussie(Lola), and we are taking her to Mexico this winter and she needs to have certain treatments required by customs to bring her across the border, my vet advised me that Heartguard and Bravecto or Nexguard are safe for her at the correct doses. Emma. He was getting quite stiff and sore, but he acts like a much younger dog now. Perros (mutacin del gen MDR1). (The Environmental Protection Agency is responsible for approving external flea and tick products.) Thank you for the research and the detailed info on each product. In the meantime, no need to give heartworm meds if its still snowy where you are, so youve got some time to figure out what to do before the mosquitoes become active again! Personally, my Roughs have sensitive skin plus I have a household cat, so Id try Frontline Gold first. Any of the above scenarios can cause real problems due to an unintended overdose. . Except for the warning about Cats who have close contact with collies, my impression was that you thought K 9 Advantix was safe and effective for Collies. Congratulations and good luck with your new dog! Thanks. Could you send the link to that article you found? GSD is an abbreviation for German Shepherd Dog , Thankyou so much for your articleso much great infoI have a 7 month mini Aussieon Symparticabut not feeling good about itshe hasnt been tested for MRD1 but I know I have to change it upthankyou again , Youre very welcome, and good luck with your pup! Though water resistant, frequent bathing or swimming (once a month or more) will reduce the collars effective time to 5 months or less. Dr. Morgan concluded her story with: Be your pets advocate. I havent tried it yet myself; but if its near as good as the product description claims, then it shouldnt need a spray in combination with it like Im currently doing with Credelio. I have an Aussie mix and desperately needed some info on this. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). I need to pivot, and looking at Frontline there are two new Frontline products to combat the flea resistance. Because I am only one person, the medication is relatively new, and it has active ingredients that are the same as more well-known medications that have been known to cause issues for many dogs, I didnt feel that I could give it an entirely glowing recommendation. User warnings Wash hands after handling the product. The tail curling and pacing lasted over a week. As with any topical, of course keep an eye out for skin irritation. Is the Frontline the one listed in the article ok in a multi dog family where there is a risk of one licking it off the other? Its worth making a phone call to see what they would recommend for your pup. Super useful research. I have been told that Advocate is safe for him at the recommended dose. I have a unique situation. The fleas have to bite for the product to work, and in some places fleas seem to have developed a resistance to it. - It is easy to administer, with no need for pre-treatment or fasting. (Most vets are going to recommend to you the products they carry in stock, but you can order online from Chewy or pet pharmacies.) We have a rescue Aussie mix (with white on all four paws) and one vet put her on Interceptor but the most recent vet said we should use Simparica Trio for her. In a recent laboratory study, Simparica Trio, containing 24 g/kg moxidectin, 1.2 mg/kg sarolaner and 5 mg/kg pyrantel, and Heartgard Plus and Interceptor Plus (n = 6) were administered in six consecutive monthly oral doses at the labeled dose rates after receiving an inoculation of 50 ZoeLA strain D. immitis L3 on day 30 [].Dogs were necropsied approximately 9 months post-inoculation and . Unacceptable for me) He is MDR1 clear. No treatment-related clinical signs were observed. Thank you so much for all your hard work and care given to writing this very informative and extremely important study greatly appreciate it , I would like to thank you for your very thorough but get to the point info of all these parasitic treatments We have a rough Collie I could not find any info on safe treatments without wading through a river of muck. I like Frank so much that I had to give him his own story. Hello, You mentioned ADVANTIX should be use with caution because of cats being around collies, but what about if I only have collies? Be prepared to answer questions about whether your dog had a previous history with seizures, has any drug sensitivities, if anything else could possibly have triggered a seizure, and if she has had any seizures since the collar was removed. Based on its limited coverage of external parasites, cautionary potential side effects label, and its non-endorsement for pregnant or nursing females, I decided I could do better for my dogs. I have a 8 yr old MAS/Aussie who is MDR1 +/+ and I have her on Trifexis and have had no issues to date. Do you know what the ingredients are in the medicated shampoo? Besides safety, Revolution is an attractive option because of its ease of application (topical squeeze-on tube) and versatility in treating heartworm, fleas, dog ticks, sarcoptic mange, and even ear mites. Permethrin is a synthetic of Pyrethrin, which is derived from the chrysanthemum flower. I have a one year old Aussie mix. Parastar Plus is not something Ive personally used, but it should be safe as one of its active ingredients is Fipronil (which is in Frontline) and the other active ingredient, Cyphenothrin, is in the same family of drugs as Permethrin. This organic powder is great for a variety of uses. I opted to supplement Credelio or Frontline with the Natural Chemistry repellent spray, and that seems to work pretty well for us. And safe travels to you and Lola in the future. Congratulations on your new puppy. Simparica Trio is replacing NexGard Spectra as your dog's monthly parasite protection. That indicates it is a strong chemical compound, so do watch for skin irritation. There weren't as many seizures reported as with Nexgard, but it did have several more reported than Bravecto. Iubitorii de animale pot comanda produsul Simparica Trio Caini (40.1 - 60 kg), 3 x comprimate masticabile la orice or din zi sau din noapte. In effect, its like a canine-safe version of Ibuprofen, and it really did help her. (Some of the links lead to peer-reviewed scientific articles, so have fun with those if you want the bare, dusty facts.). Frontline Shield has Permethrin and Pyriproxifen, so my concern would be that those 2 ingredients together would be stronger and potentially cause skin irritation. Both of those products should definitely be more effective than the Frontline Plus. Emily, thanks for a very helpful and informative article there were no side. 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